Oral Plus Topical Administration of Enrofloxacin-Hydrochloride-Dihydrate for the Treatment of Unresponsive Canine Pyoderma. A Clinical Trial

An outpatient clinical trial on unresponsive deep-bacterial canine pyoderma (UDCP), without a control group, is presented.The chosen treatment was implemented with a new crystal-solvate of enrofloxacin (enrofloxacin HCl-2H2O or enro-C), in a dual scheme, i.e., 10 mg/kg/day PO, plus its topical administration, prepared as 0.5% in an alginate gel, th

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The role of monocytes and macrophages in idiopathic inflammatory myopathies: insights into pathogenesis and potential targets

Idiopathic inflammatory myopathies (IIMs) are heterogeneous autoimmune disorders characterized by muscle inflammation, weakness, and extramuscular manifestations such as interstitial lung disease, skin rash, arthritis, dysphagia, myocarditis and other systemic organ involvement.Although T and B cells have historically been central to the understand

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Flux predictions in the transition region incorporating the effects from propagation of cosmic rays in the Galactic magnetic field

Galactic cosmic rays (GCRs) and (anisotropically injected) extragalactic cosmic rays (EGCRs) are both affected by the Galactic magentic field (GMF) on their voyage to Dog Coats Earth at energies pertaining to the transition from GCRs to EGCRs, such that their flux, composition and arrival directions are modified.GCRs increasingly leak from the Gala

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